Cinnamic acids and derivatives
Medchemexpress LLC 4-chlorocinnamic acid | 1615-02-7 | MFCD00004396 | 100.0% | 182.61 g/mol | C9H7ClO2 | 25g
4-Chlorocinnamic acid is a derivative of Cinnamic acid (HY-N0610A) 4-Chlorocinnamic acid inhibits the monophenolase and diphenolase activities of mushroom tyrosinase with IC50 values of 0 477 mM and 0 229 mM respectively 4-Chlorocinnamic acid inhibits the mycelial growth of Colletotrichum gloeosporioides 4-Chlorocinnamic acid exhibits anticonvulsant activity against acute epilepsy induced by pentylenetetrazol[1][2][3][4]
Medchemexpress LLC N-methyl-3'-hydroxycoclaurine hydrochloride | 138644-99-2 | 351.82 | C18H22ClNO4 | 500 UG
N-Methyl-3'-hydroxycoclaurine hydrochloride is the hydrochloride salt of a coclaurine-related small molecule described as an impurity and used in research and synthetic chemistry as a drug intermediate or analytical reference. The compound is provided for laboratory and drug-discovery workflows where related intermediates, impurities, or standards are required.
- Hydrochloride salt form for handling and formulation consistency.
- Small-molecule impurity related to coclaurine chemistry.
- Suitable for use as a drug intermediate or analytical standard.
- Molecular formula C18H22ClNO4 and molecular weight 351.82.
- CAS number 138644-99-2 for unambiguous identification.
- Certificate of analysis provides storage and batch-specific purity information.
Medchemexpress LLC Dodeca-2E,4E,8Z,10Z/E-N-tetraenoic acid isobutylamide | 866602-52-0 | 98.5% | 247.38 | C16H25NO | 5mg
Dodeca-2E 4E 8Z 10Z/E-N-tetraenoic acid isobutylamide is a brain-penetrant substance and the main alkamide in Echinacea preparations which might be used for research of common cold and various upper respiratory infections[1]
Accela Chembio Inc 4-hydroxy-3 | 5-dimethoxycinnamic Acid | Predominantly Trans | 100g | 530-59-6 | MFCD00004401 | 97+% | Shelf Life: 1080 Days | Light Sensitive
4-hydroxy-3 | 5-dimethoxycinnamic Acid | Predominantly Trans | 100g | 530-59-6 | MFCD00004401 | 97+% | Shelf Life: 1080 Days | Light Sensitive
Medchemexpress LLC MRL-494 hydrochloride | 2699937-04-5 | 98.6% | 100 MG
MRL-494 hydrochloride is an antibacterial agent that acts as an inhibitor of β-barrel assembly machine A (BamA). It is impervious to efflux and the outer membrane permeability barrier, and lethally disrupts the cytoplasmic membrane. It inhibits outer membrane proteins (OMPs) biogenesis by targeting BamA, demonstrating strong anti-microbial properties against various bacteria.
- Acts as an inhibitor of β-barrel assembly machine A (BamA)
- Impervious to efflux and outer membrane permeability barrier
- Lethally disrupts the cytoplasmic membrane
- Inhibits outer membrane proteins (OMPs) biogenesis
- Strong anti-microbial properties against Gram-positive bacteria (e.g., *Staphylococcus aureus* with MIC of 12.5 μM)
- Strong anti-microbial properties against Gram-negative bacteria (e.g., *E. coli* with MIC of 25 μM)
eMolecules 40803-53-0 | 5-Bromo-2-methoxycinnamic acid | Oakwood Chemical | MFCD00017596 | 257.083 | C10H9BrO3 | 97.000 | COc1ccc(Br)cc1\C=C\C(O)=O | 1g | 537672218
5-Bromo-2-methoxycinnamic acid | Oakwood Chemical | 40803-53-0 | MFCD00017596 | 257.083 | C10H9BrO3 | 97.000 | COc1ccc(Br)cc1\C=C\C(O)=O | 1g | 537672218
Medchemexpress LLC Tyrphostin 8 | 3785-90-8 | MFCD00020189 | 98.0% | 170.17 g/mol | C10H6N2O | 50 MG
Tyrphostin 8 is a small-molecule research compound that acts as a weak epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor and a more potent inhibitor of the serine/threonine phosphatase calcineurin. Supplied as a solid for laboratory research, it is intended for research use only.
- Small-molecule inhibitor of EGFR and calcineurin (EGFR IC50 560 μM; calcineurin IC50 21 μM).
- High purity: 98.0%.
- Chemical formula C10H6N2O; molecular weight 170.17 g/mol.
- CAS number 3785-90-8.
- Soluble in DMSO at ≥ 100 mg/mL.
- Appearance: light yellow to yellow solid.
- Storage: store at 4°C under nitrogen; in solvent store at -80°C (6 months) or -20°C (1 month).
- For research use only; not for human or clinical applications.
Cayman Chemical m-CoumarIc AcId 5g
An active metabolite of polyphenols; inhibits cumene hydroperoxide-induced oxidation of DNA (IC50 = 54.7 µM); induces neurite outgrowth of fetal rat hippocampal neurons at 10 µM; induces apoptosis and cell cycle arrest at the G0/G1 phase in HeLa cells at 5 and 10 mM, respectively; increases locomotor activity in mice at 3 mmol/kg
TARGETMOL CHEMICALS INC BISDEMETHOXYCURCUMIN 50MG
Also available in 5 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Bisdemethoxycurcumin (Curcumin III) is a natural demethoxy derivative of curcumin. It is a potent activator of macrophage phagocytosis interacting with 1(alpha) 25-dihydroxy vitamin D3 to stimulate amyloid-(beta) clearance by macrophages (optimal stimulation at 100 nM BDMC) [1]. More stable than curcumin in physiological media BDMC suppresses proliferation of cancer cells [2]. It down-regulates the transcriptional coactivator p300 suppressing the Wnt/(beta)-catenin pathway and inhibits LPS induction of iNOS expression [3]. purity: 99%
Matrix Scientific 4-(TRIFLUOROMETHYL)CINNAMI-25G
4-(Trifluoromethyl)cinnamic acid, 98%; 25g,C10H7F3O2, MFCD00002696, mw 216.16, [16642-92-5]
TARGETMOL CHEMICALS INC RUXOLITINIB S ENANTIOMER 50MG
Also available in 5 mg 10 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Ruxolitinib S enantiomer (INCB18424) is the S-enantiomer of Ruxolitinib. Ruxolitinib is the first potent selective JAK1/2 inhibitor. purity: 99%
TARGETMOL CHEMICALS INC CIPROPRIDE S ENANTIOMER 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Cipropride S enantiomer is the S enantiomer of cipropride which is an antiemetic drug. purity: 99%
TARGETMOL CHEMICALS INC CINANSERIN HYDROCHLORIDE 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Cinanserin hydrochloride (SQ 10643) is a high affinity antagonist of the 5-HT2 receptor (Ki 41 nM) and a 3C-like protease inhibitor of severe acute respiratory syndrome coronavirus. purity: 99%
eMolecules 160434-49-1 | 3-Bromo-4-fluorocinnamic acid | Ambeed | MFCD00143095 | 245.047 | C9H6BrFO2 | 98.000 | OC(=O)\C=C\c1ccc(F)c(Br)c1 | 1g | 527443839
3-Bromo-4-fluorocinnamic acid | Ambeed | 160434-49-1 | MFCD00143095 | 245.047 | C9H6BrFO2 | 98.000 | OC(=O)\C=C\c1ccc(F)c(Br)c1 | 1g | 527443839